Provigil Mania

G Letter to the Editor Print Friendly Modafinil-Induced Mania in a Patient with Bipolar Affective Disorder Return August 5, 2007 To the Editor: Modafinil has been approved for the treatment of excessive daytime sleepiness associated with narcolepsy, shift-work sleep disorder, and obstructive sleep apnea/hypopnea syndrome. It is sparingly to slightly soluble in methanol and acetone PROVIGIL tablets contain 100 mg or 200 mg of modafinil and the following inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone, and pregelatinized starch Depression is much more common in the life course of people with bipolar disorder than mania or mixed states. Cephalon recommends that doctors should consider stopping Provigil. Doctors prescribe modafinil, sold under the brand name Provigil, to improve wakefulness in adults who are experiencing excessive sleepiness as a result of obstructive sleep apnea, shift work sleep. The psychiatric history and clinical course of this patient suggest that the mania is likely to be related to modafinil use and, to our knowledge, this is the first report of late onset mania related to modafinil use in the literature Modafinil was developed to promote wakefulness in people with narcolepsy and other sleep disorders, but the stimulant’s reported ability to improve thinking and memory has led to its off-label use as a “smart drug” by people without sleep problems.. provigil mania Heart disease—Use with caution. I would really like to get off Adderall, which I primarily use to keep me awake. unfortunately for me though, it hasn’t been super affective for my depressive symptoms. He cautioned about the similar rates of mania-switching found in the modafinil and placebo groups, as the modafinil dose in the study was relatively low (mean dose 177 mg/day). Unfortunately, few established treatments are available, and new ones are needed. Consider discontinuing PROVIGIL if psychiatric excessive sleepiness associated with narcolepsy, obstructive sleep apnea symptoms develop Modafinil is a white to off-white, crystalline powder that is practically insoluble in water and cyclohexane. What is Modafinil? To our knowledge, we present the first case report of an individual being treated and stabilized with olanzapine monotherapy for this condition. it’s marginally better but i’m still sleepy a lot. The recommended dosage of modafinil for treating sleep disorders is 200 mg, according to the product labeling information Nuvigil & Provigil do what they are supposed to do, but on balance the side effects are miserable, even after years. In the study, modafinil decreased depressive symptoms and increased remission rates. Left ventricular hypertrophy (heart disease), history of or. We describe the case of a 53-year-old African American male admitted to an inpatient psychiatric. Many, but not all, patients had a prior psychiatric history. I don't want to be on antipsychotics anymore but sometimes I seriously just can't wake up when I'm at my worst for me, it hasn’t really triggered mania. Read this Medication Guide before you start taking PROVIGIL and each time you get a refill. Psychiatrists and others have used Provigil off label (non-FDA approved reasons) for other indications such as an adjunct. 25. PROVIGIL (pro-vij-el) C-IV (modafinil) Tablets. No adverse effects or mood changes were noted.CONCLUSIONS: Modafinil may be a well-tolerated and effective alternative to conventional stimulants in the treatment of hypersomnia, especially in bipolar disorder, where there is considerable risk of switch to mania with stimulant medications Modafinil is a prescription drug that promotes wakefulness and can be used to treat conditions such as obstructive sleep apnea, hypopnea syndrome (OSAHS), narcolepsy, and shift work sleep disorder Modafinil is available under the following different brand names: Provigil. The effectiveness rate was. 30AM, take my Provigil, then by about 9 or 10AM, I had the energy I needed. Caution should be exercised when Provigil is given to patients with a history of psychosis, depression, or mania. Frye, M.D., et al. I would really like to get off Adderall, which I primarily use to keep me awake. It is not known how modafinil will affect these conditions. Am J Psychiatry 2005;162(4):813-4. CNS Drugs 1998;9(4):311-24. it feels just like drinking extra coffee. Modafinil is associated with the onset or worsening of psychotic symptoms or manic symptoms (including hallucinations, delusions, agitation or mania).